anserine
Anserine is a histidine-containing dipeptide found naturally in chicken and other meats, closely related to carnosine. It functions as an antioxidant and may help buffer muscle pH during exercise, potentially reducing exercise-induced muscle damage and oxidative stress. Research suggests it may enhance athletic performance and support recovery when consumed through dietary sources or supplementation.
Lab Notes — Research Studies
01 Anserine Reverses Exercise-Induced Oxidative Stress and Preserves Cellular Homeostasis in Healthy Men
Study found that anserine supplementation effectively reduced oxidative stress markers following exercise and helped maintain cellular balance in healthy male subjects.
View Study ((PubMed))02 Optimized Curcumin, Pomegranate Extract, and Methylsulfonylmethane Reduce Acute, Systemic Inflammatory Response to a Half-Marathon Race
Combined supplementation including compounds that work synergistically with anserine-type effects reduced inflammatory markers following endurance running events.
View Study ((PubMed))Formula — Benefits & Dosage
⚗️ Effects
- Athletic Performance: Demonstrated measurable improvements in cycling power when consumed 40 minutes pre-exercise
- Dose-Response: Effective at approximately 46.4 mg/kg body weight of histidine dipeptides (anserine + carnosine)
- Timing Matters: Pre-exercise consumption (40 minutes prior) appears optimal for performance benefits
- Natural Sources: Chicken soup and meat-based sources provide bioavailable forms of anserine
💉 Dosage & Administration
- Research Dose: 46.4 mg per kilogram of body weight for performance enhancement
- Food-Based: One bowl of chicken soup consumed 40 minutes before exercise showed benefits
- Natural Intake: Regular consumption of chicken and meat products provides baseline dietary anserine
- Timing: Pre-exercise consumption appears more effective than post-exercise for immediate performance gains
⚠️ Side Effects
- Minimal Side Effects: Studies and user reports indicate anserine is generally well-tolerated
- Food Source Safety: When consumed through natural sources like chicken soup, virtually no adverse effects reported
- Long-term Safety: Has a long history of safe consumption through dietary sources
- No Major Concerns: Research papers do not highlight significant safety issues at recommended doses
📦 Availability & Sourcing
- Dietary Sources: Readily available through chicken, turkey, and other poultry products
- Supplementation: Can be obtained through carnosine/anserine supplements or chicken-based broths
- Natural Access: No prescription required; available through regular food consumption or over-the-counter supplements
Reaction Log — User Experiences
Users report noticeable improvements in exercise performance and recovery, with one study showing a 5% increase in cycling power. The compound appears well-tolerated with minimal side effects when consumed through natural food sources like chicken soup.
Synthesis — Related Compounds
⚠️ IMPORTANT DISCLAIMER
This information is for educational and research purposes only. anserine may not be approved for human use. Always consult a qualified healthcare professional before using any supplements or research compounds. We do not guarantee accuracy or completeness of information presented.