selank
Selank is a Russian peptide derived from tuftsin with anxiolytic and nootropic properties. It modulates GABA and serotonin systems, reducing anxiety while enhancing cognitive function without sedation or dependency.
Lab Notes — Research Studies
01 Expression of inflammation-related genes in mouse spleen under tuftsin analog Selank
Found significant changes in 34 inflammation-related genes, confirming Selank's immune-regulating role.
View Study ((ScienceDirect))02 The temporary dynamics of inflammation-related genes expression under tuftsin analog Selank action
Selank and its Gly-Pro fragment similarly influenced multiple immune-related genes.
View Study ((ScienceDirect))03 Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission
Selank induces changes in GABA neurotransmission genes, suggesting a mechanism similar to benzodiazepines.
View Study ((Frontiers))04 Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity
Selank functions as a positive allosteric modulator of GABA receptors, offering anxiety relief.
View Study ((Institute of Molecular Genetics))05 Physiological Effects of Selank and Its Fragments
Analyzed data on Selank's benefits including anxiety reduction, cognitive enhancement, and immune stimulation.
View Study ((Institute of Molecular Genetics))06 Use of Selank to correct measures of integrative brain activity in adult rats from Antenatal Hypoxia
Selank improved sensory attention, learning, and behaviors in rats while restoring serotonin balance.
View Study ((Institute of Cell Biophysics))07 The effectiveness of selank in the treatment of adjustment disorder
Selank significantly reduced symptoms of Adjustment Disorder including somatic complaints.
View Study ((Ukrainian Scientific Research Institute))08 Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety
Selank works similarly to benzodiazepines and can enhance diazepam's effects under chronic stress.
View Study ((Institute of Molecular Genetics))09 Selank and Short Peptides of the Tuftsin Family in the Regulation of Adaptive Behavior in Stress
Evaluated peptide compounds including Selank for emotional and antistress effects.
View Study ((V. V. Zakusov Research Institute))Formula — Benefits & Dosage
⚗️ Effects
- Fast Acting: Effects often noticed within hours.
- No Tolerance: Maintains effectiveness with continued use.
- Versatile: Benefits both anxiety and cognitive function.
💉 Dosage & Administration
- Typical Range: 250-500mcg intranasally, 1-3 times daily.
- Subcutaneous: Can also be injected subcutaneously.
- Daily Use: Can be used consistently without tolerance.
⚠️ Side Effects
- Very Well Tolerated: Few side effects reported.
- Nasal Irritation: Minor with intranasal use.
- Fatigue: Some report tiredness at higher doses.
- Excellent Safety: No significant adverse effects documented.
📦 Availability & Sourcing
- Research Chemical: Available from peptide suppliers.
- Russian Origin: Approved medication in Russia.
- Nasal Spray: Often sold as premade nasal spray.
Reaction Log — User Experiences
Highly regarded for anxiety relief without sedation or addiction. Users report calm focus and improved stress resilience. Often preferred over semax for anxiety-prone individuals.
Synthesis — Related Compounds
⚠️ IMPORTANT DISCLAIMER
This information is for educational and research purposes only. selank may not be approved for human use. Always consult a qualified healthcare professional before using any supplements or research compounds. We do not guarantee accuracy or completeness of information presented.