ghk-cu
GHK-Cu (Copper peptide) is a naturally occurring tripeptide with copper bound to it. It promotes wound healing, collagen synthesis, and has anti-aging properties. Used topically for skin rejuvenation and systemically for tissue repair.
Lab Notes — Research Studies
01 In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+
GHK-Cu increases extracellular matrix accumulation in wounds in vivo, potentially promoting wound repair and healing.
View Study ((Journal of Clinical Investigation))02 The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ stimulates matrix metalloproteinase-2 expression by fibroblast cultures
GHK-Cu stimulates MMP-2 expression in wound fibroblasts, promoting connective tissue production and remodeling.
View Study ((ScienceDirect))03 Stimulation of sulfated glycosaminoglycan synthesis by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+
GHK-Cu stimulates glycosaminoglycan synthesis in human fibroblasts, potentially contributing to its wound healing properties.
View Study ((ScienceDirect))04 Glycyl-L-histidyl-L-lysine-Cu2+ attenuates cigarette smoke-induced pulmonary emphysema and inflammation by reducing oxidative stress pathway
GHK-Cu treatment reduces cigarette smoke-induced emphysema and inflammation by reducing oxidative stress, offering potential for COPD.
View Study ((Frontiers))05 The Human Tripeptide GHK-Cu in Prevention of Oxidative Stress and Degenerative Conditions of Aging
GHK tripeptide shows potential as a therapeutic agent against age-associated neurodegeneration and cognitive decline.
View Study ((Wiley Online Library))06 Effects of GHK-Cu on MMP and TIMP Expression, Collagen and Elastin Production, and Facial Wrinkle Parameters
GHK-Cu with nano-carriers significantly increases collagen and elastin production in human dermal fibroblasts, reducing facial wrinkle volume.
View Study ((Journal of Aging Science))07 Self-Assembled Fluorescent and Antibacterial GHK-Cu Nanoparticles for Wound Healing Applications
Self-assembled GHK-Cu nanoparticles show good biocompatibility and enhanced wound healing applications, offering antibacterial properties.
View Study ((Wiley Online Library))Formula — Benefits & Dosage
⚗️ Effects
- Visible Results: Skin improvements often noticeable within weeks.
- Versatile Application: Effective both topically and systemically.
- Well-Researched: Substantial body of research supporting benefits.
💉 Dosage & Administration
- Topical: Applied as serum, typically 1-2% concentration.
- Injectable: 1-2mg subcutaneously daily or several times per week.
- Duration: Cycles of 4-8 weeks are common.
⚠️ Side Effects
- Generally Very Safe: One of the best-tolerated peptides.
- Skin Irritation: Rarely, topical application may cause mild irritation.
- Injection Site Reactions: Minor bruising or redness possible.
📦 Availability & Sourcing
- Widely Available: Found in skincare products and from peptide suppliers.
- Multiple Forms: Available as serums, creams, and injectable powder.
- Reasonable Cost: Relatively affordable compared to many peptides.
Reaction Log — User Experiences
Users consistently report improvements in skin quality, wound healing, and hair growth. Both topical and injectable forms are popular. Considered one of the safer peptides.
Synthesis — Related Compounds
⚠️ IMPORTANT DISCLAIMER
This information is for educational and research purposes only. ghk-cu may not be approved for human use. Always consult a qualified healthcare professional before using any supplements or research compounds. We do not guarantee accuracy or completeness of information presented.